AFFILIATION:
Magnetic Resonance Center and Department of Chemistry
University of Florence

ADDRESS:
Via L. Sacconi 6
50019 Sesto Fiorentino, (FI) -Italy

CONTACTS:
Tel: +39 055 4574265
e-mail: pierattelli[at]cerm.unifi.it ; roberta.pierattelli[at]unifi.it

RESEARCH PROFILES:
ORCID_ID profile
Google scholar profile
University of Florence page

Roberta Pierattelli graduated in Chemistry at the University of Florence (Italy) and received a PhD in Chemistry at the same university in 1995. After a postdoctoral year at the Department of Chemistry of the University of Southampton (United Kingdom), she was appointed as a Researcher at the University of Florence, where she became Associate Professor of Chemistry and, since 2017, Full Professor of Chemistry. Her research interests are mainly related to applications of NMR spectroscopy to the study of the structure and function of proteins and their interactions.

Full CV

RESEARCH FIELDS:

NMR; structural biology; biophysics; metalloproteins; intrinsically disordered proteins; protein-protein interactions

SELECTED PUBLICATIONS:

1. Gonzalez, L.J.; Hita, F.J.; Pontoriero, L; Pierattelli, R; Binolfi, A; Vila, A.J., Periplasmic Protein Quality Control at Atomic Level in Live Cells, Nat. Comm., 2025, 16, 8366.

2. Bolognesi, T.; Schiavina, M.; Felli, I.C., Pierattelli, R. NMR Insights on Multidomain Proteins: the Case of the SARS-CoV-2 Nucleoprotein, Prog. NMR Spetros., 2025, 148-149, 101577.

3. Bracaglia, L.; Oliveti, S.; Felli, I.C.; Pierattelli, R. Decoding order and disorder in proteins by NMR spectroscopy, J. Am. Chem. Soc. 2025, 147, 13146-13157.

4. Tino, A.S.; Quagliata, M.; Schiavina, M.; Pacini, L.; Papini, A.M.; Felli, I.C.; Pierattelli, R. Revealing the Potential of a Chimaera: a Peptide-Peptide Nucleic Acid Molecule Designed To Interact with the SARS-CoV-2 Nucleocapsid Protein, Angew. Chem., 2025, 64, e202420134.

5. Knödlstorfer, S.; Schiavina, M.; Rodella, M.A.; Ledolter, K.; Konrat, R.; Pierattelli, R.; Felli, I.C. Disentangling the complexity in protein complexes using complementary isotope-labeling and multiple-receiver NMR spectroscopy, J. Am. Chem. Soc., 2024, 146, 27983-27987.

6. Schiavina, M.; Bracaglia, L.; Rodella, M.A.; Kümmerle, R.; Kornat, R.; Felli, I.C.; Pierattelli, R. Optimal 13C NMR Investigation of Intrinsically Disordered Proteins at 1.2 GHz, Nat. Protocols, 2024, 19, 406–440.

7. Felli, I.C.; Pierattelli, R. 13C direct detected NMR for challenging systems, Chem Rev. 2022, 122, 9468-9496.

8. Bonaccorsi, M.; Knight, M.J.; Le Marchand, T.; Dannatt, H.R.W.; Schubeis, T.; Salmon, L.; Felli, I.C.; Emsley, L.; Pierattelli, R.; Pintacuda, G. Multimodal Response to Copper Binding in Superoxide Dismutase Dynamics. J. Am. Chem. Soc., 2020, 142, 19660-19667.

9. Bertarello, A.; Benda, L.; Sanders, K.J.; Pell, A.J.; Knight, M.J.; Pelmenschikov, V.; Gonnelli, L.; Felli, I.C.; Kaupp, M.; Emsley, L.; Pierattelli, R.; Pintacuda, G. Picometer Resolution Structure of the Coordination Sphere in the Metal-Binding Site in a Metalloprotein by NMR. J. Am. Chem. Soc. 2020, 142,16757-16765.

10. Pontoriero, L.; Schiavina, M.; Murrali, M.G.; Pierattelli, R.; Felli, I.C. Monitoring the Interaction of α‐Synuclein with Calcium Ions through Exclusively Heteronuclear Nuclear Magnetic Resonance Experiments, Angew. Chem. Int. Ed. 2020, 132, 18696-18704.