Full Professor
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AFFILIATION: ADDRESS: CONTACTS: RESEARCH PROFILES: |
Roberta Pierattelli graduated in Chemistry at the University of Florence (Italy) and received a PhD in Chemistry at the same university in 1995. After a postdoctoral year at the Department of Chemistry of the University of Southampton (United Kingdom), she was appointed as a Researcher at the University of Florence, where she became Associate Professor of Chemistry and, since 2017, Full Professor of Chemistry. Her research interests are mainly related to applications of NMR spectroscopy to the study of the structure and function of proteins and their interactions.
RESEARCH FIELDS: NMR; structural biology; biophysics; metalloproteins; intrinsically disordered proteins; protein-protein interactions
SELECTED PUBLICATIONS: Mateos, B.; Conrad-Billroth, C.; Schiavina, M.; Beier, A.; Kontaxis, G.; Konrat, R.; Felli, I.C.; Pierattelli, R. The Ambivalent Role of Proline Residues in an Intrinsically Disordered Protein: From Disorder Promoters to Compaction Facilitators. J. Mol. Biol. 2020, [Epub ahead of print] Kukic, P.; Lo Piccolo, G.M.; Nogueira, M.O.; Svergun, D.I.; Vendruscolo, M.; Felli, I.C.; Pierattelli, R. The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions. Sci Rep. 2019, 9, 5822. Mateos, B.; Konrat, R.; Pierattelli, R.; Felli, I.C. NMR characterization of long-range contacts in intrinsically disordered proteins from paramagnetic relaxation enhancement in 13C direct-detected experiments. CheBioChem. 2019, 20, 335-339. 4. Nogueira, M.O.; Hošek, T.; Calçada, E.O.; Castiglia, F.; Massimi, P.; Banks, L.; Felli, I.C.; Pierattelli, R. Monitoring HPV-16 E7 Phosphorylation Events. Virology, 2017, 503,70-75 (IF2015 3.200). 5. Hošek, T.; Calçada, E.O.; Nogueira, M.O.; Salvi, M.; Pagani, T.D.; Felli, I.C.; Pierattelli, R.. Structural and Dynamic Characterization of the Molecular Hub Early Region 1A (E1A) from Human Adenovirus. Chemistry. 2016, 22,13010-3. 6. Piai, A.; Calçada, E.O.; Tarenzi, T.; del Grande, A.; Varadi, M.; Tompa, P.; Felli, I. C.; Pierattelli, R. Just a Flexible Linker? The Structural and Dynamic Properties of CBP-ID4 as Revealed by NMR Spectroscopy. Biophys. J., 2016, 110, 372-81. 7. Felli, I. C.; Pierattelli, R.; Spin-state-selective Methods in Solution- and Solid-state Biomolecular 13C NMR, Prog. NMR Spectrosc. 2015, 84, 1-13. 8. Felli, I. C.; Gonnelli, L.; Pierattelli, R. In-cell 13C NMR Spectroscopy for the Study of Intrinsically Disordered Proteins. Nature Protoc. 2014. 9, 2005-2016. 9. Knight, M. J.; Felli, I. C.; Pierattelli, R.; Emsley, L.; Pintacuda, G. Magic Angle Spinning NMR of Paramagnetic Proteins. Acc. Chem. Res. 2013, 46, 2108-2116. 10. Knight, M. J.; Pell, A. J.; Bertini, I.; Felli, I. C.; Gonnelli, L.; Pierattelli, R.; Hermann, T.; Emsley, L.; Pintacuda, G. Structure and Backbone Dynamics of a Microcrystalline Metalloprotein by Solid-State NMR. Proc. Natl. Acad. Sci. USA 2012, 109, 11095-11100.
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