Research Fellow
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Gaia Meoni was born in 1991. She obtained a Master Degree in Molecular Biology and Genetics at the University of Pavia (Italy) in 2015. The same year she won a Ph.D scholarship for the International Doctorate in Structural Biology at the University of Florence. During the Ph.D. she started working on NMR-based metabolomic applications for the chemical characterization of several animal biofluids, such as urine, serum, and saliva, in order to study at molecular level and to shed light on the biochemical pathways involved in pathologies, such as Parkinson's disease and viral and bacterial infections, such as hepatitis C and B, periodontal diseases and bacterial sepsis. During the Ph.D. she also studied agro-food matrices (such as, olives and olive oil, green and roasted coffee, and cow's milk) with the aim to innovatively explore the potential of NMR for the chemical assessment of food quality and traceability. Thanks to the experience gained applying NMR metabolomics for the study and the characterization of food matrices, in 2018 she earned the Ph.D. with the vote of excellent cum laude and she obtained a postdoctoral position at C.I.R.M.M.P. In 2019, she was the winner of the “Faber 2” prize (a project of the di Fondazione CR Firenze, Confindustria Firenze and Fondazione per la Ricerca e l’Innovazione, promoted by Università degli Studi di Firenze and Città Metropolitana di Firenze), which aims to promote the scientific innovation and the enhancement of the young talents in Tuscany. Thanks to this funding she started working as a postdoc at Giotto Biotech S.r.l. During the COVID-19 pandemic and the resulting growing global interest in the mechanism of infection of SARS-CoV-2, she actively participated in the COMETA project, funded by the region of Tuscany, winning a post-doctoral fellowship at the University of Florence, at the department of Chemistry. This project aimed to provide the characterization of the metabolic and lipoproteomic profiles of COVID-19 patients. She is currently working as research fellow (RtdA) at the Department of Chemistry of the University of Florence.
RESEARCH FIELDS: Metabolomics, foodomics, multivariate statistics, NMR
SELECTED PUBLICATIONS: Niero G, Meoni G, Tenori L, Luchinat C, Visentin G, Callegaro S, et al. Grazing affects metabolic pattern of individual cow milk. Journal of Dairy Science. 2022 Dec 1;105(12):9702–12. https://doi.org/10.3168/jds.2022-22072 Vignoli A, Meoni G*, Ghini V, Di Cesare F, Tenori L, Luchinat C, et al. NMR-Based Metabolomics to Evaluate Individual Response to Treatments. Handb Exp Pharmacol. 2022 Nov 2; Ghini V, Meoni G*, Pelagatti L, Celli T, Veneziani F, Petrucci F, et al. Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients. PLoS Pathog. 2022 Apr;18(4):e1010443. https://doi.org/10.1371/journal.ppat.1010443. Meoni G, Tenori L, Schade S, Licari C, Pirazzini C, Bacalini MG, et al. Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson’s disease patients. NPJ Parkinsons Dis. 2022 Feb 8;8(1):14. https://doi.org/10.1038/s41531-021-00274-8 Bobbo T, Meoni G*, Niero G, Tenori L, Luchinat C, Cassandro M, et al. Nuclear magnetic resonance spectroscopy to investigate the association between milk metabolites and udder quarter health status in dairy cows. Journal of Dairy Science. 2022;105(1):535–48. https://doi.org/doi.org/10.3168/jds.2021-20906. Meoni G, Luchinat C, Gotti E, Cadena A, Tenori L. Phenotyping Green and Roasted Beans of Nicaraguan Coffea Arabica Varieties Processed with Different Post-Harvest Practices. Applied Sciences. 2021 Jan;11(24):11779. https://doi.org/10.3390/app112411779 Meoni G, Ghini V, Maggi L, Vignoli A, Mazzoni A, Salvati L, et al. Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab. PLOS Pathogens. 2021 Feb 1;17(2):e1009243. https://doi.org/10.1371/journal.ppat.1009243. Dourou AM, Brizzolara S, Meoni G, Tenori L, Famiani F, Luchinat C, et al. The inner temperature of the olives (cv. Leccino) before processing affects the volatile profile and the composition of the oil. Food Research International. 2020 Mar 1;129:108861. https://doi.org/10.1016/j.foodres.2019.108861 Meoni G, Lorini S, Monti M, Madia F, Corti G, Luchinat C, et al. The metabolic fingerprints of HCV and HBV infections studied by Nuclear Magnetic Resonance Spectroscopy. Scientific Reports. 2019 Mar 11;9(1):4128. https://doi.org/10.1038/s41598-019-40028-4 |